Safety and Tolerability of Transcutaneous Vagus Nerve Stimulation in Humans; a Systematic Review
Redgrave, J., et al. “Safety and Tolerability of Transcutaneous Vagus Nerve Stimulation in Humans; a Systematic Review.” Brain Stimulation, vol. 11, no. 6, 2018, pp. 1225–1238., doi:10.1016/j.brs.2018.08.010
This article analyzes 51 studies with a total of 1,322 subjects to determine how safe transcutaneous vagus nerve stimulation is. The subjects were receiving electrical currents through their skin. The most common side effects were skin irritation at the electrode site, a headache, or nasal inflammation seen in a cold. Serious side effects were rare and none could be confirmed to be due to the treatment. Therefore, the article confirms that transcutaneous vagus nerve stimulation is safe for humans.